name: | CalciumFolinate |
ATC code: | V03AF03 | route: | intravenous |
n-compartments | 2 |
Calcium folinate (leucovorin calcium) is a medication used to reduce the toxic effects of folic acid antagonists such as methotrexate. It is also used in combination with 5-fluorouracil in the treatment of colorectal cancer. Calcium folinate is approved and widely used today as a rescue agent in chemotherapy protocols.
Pharmacokinetic parameters reported in healthy adult volunteers after intravenous administration.