.Pharmacolibrary.Drugs.ATC.V.V03AF08 .Pharmacolibrary.Drugs.ATC.V.V03AF08| name: | Palifermin | |
| ATC code: | V03AF08 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 60 | mg |
| volume of distribution: | 6.9 | L |
| clearance: | 1890 | mL/h/kg |
| other parameters in model implementation | ||
Palifermin is a recombinant human keratinocyte growth factor (KGF) that is used to decrease the incidence and duration of severe oral mucositis in patients with hematologic malignancies undergoing high-dose chemotherapy and stem cell transplantation. It is FDA approved and in current clinical use.
Pharmacokinetic parameters reported in adults with hematologic malignancies receiving high-dose chemotherapy and hematopoietic stem cell transplantation.