.Pharmacolibrary.Drugs.ATC.V.V03AF10 .Pharmacolibrary.Drugs.ATC.V.V03AF10| name: | SodiumLevofolinate |
| ATC code: | V03AF10 | route: | intravenous |
| n-compartments | 1 |
Sodium levofolinate, also known as levoleucovorin, is the active (S)-enantiomer of folinic acid. It is used as a chemoprotective agent to reduce the toxicity of methotrexate therapy and to enhance the efficacy of fluoropyrimidine-based chemotherapy. Approved for medical use, it is administered parenterally, often intravenously, as a rescue agent in cancer chemotherapy regimens.
Pharmacokinetic estimate for adults (no published human PK model located, see notes).