.Pharmacolibrary.Drugs.ATC.V.V03AX04 .Pharmacolibrary.Drugs.ATC.V.V03AX04| name: | Difelikefalin |
| ATC code: | V03AX04 | route: | intravenous |
| n-compartments | 2 |
Difelikefalin is a selective kappa opioid receptor agonist, used for the treatment of moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis. It is approved for medical use and acts peripherally with minimal crossing of the blood-brain barrier, reducing the risk of central opioid side effects.
Pharmacokinetic parameters reported for adult patients undergoing hemodialysis, following intravenous administration.