.Pharmacolibrary.Drugs.ATC.V.V03AZ01

Information

name:Ethanol
ATC code:V03AZ01
route:oral
n-compartments1

Ethanol (ethyl alcohol) is a psychoactive substance commonly found in alcoholic beverages. It acts as a central nervous system depressant. Medically, ethanol has been used as an antidote for methanol and ethylene glycol poisoning, and as a disinfectant. It is not prescribed as a therapeutic agent for routine patient use in current practice outside its role in toxicology.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult humans after oral administration of ethanol. There is considerable interindividual variability due to factors such as sex, age, body composition, and chronic alcohol use.

References

  1. Büsker, S, et al., & Fuhr, U (2023). Population Pharmacokinetics as a Tool to Reevaluate the Complex Disposition of Ethanol in the Fed and Fasted States. Journal of clinical pharmacology 63(6) 681–694. DOI:10.1002/jcph.2205 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36688276

  2. Knych, HK, et al., & McKemie, DS (2024). Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses. Drug testing and analysis None –. DOI:10.1002/dta.3803 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39279026

  3. Imbert, B, et al., & Simon, N (2016). Population Pharmacokinetics of High-Dose Oxazepam in Alcohol-Dependent Patients: Is There a Risk of Accumulation?. Therapeutic drug monitoring 38(2) 253–258. DOI:10.1097/FTD.0000000000000262 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26580099

Revisions


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