.Pharmacolibrary.Drugs.ATC.V.V04CE03 .Pharmacolibrary.Drugs.ATC.V.V04CE03| name: | Methacetin13c | |
| ATC code: | V04CE03 | route: | intravenous |
| compartments: | 1 | |
| dosage: | 2 | mg |
| volume of distribution: | 0.62 | L |
| clearance: | 23 | mL/min/kg |
| other parameters in model implementation | ||
Methacetin (13C) is a stable isotope-labeled derivative of methacetin used as a diagnostic agent for assessing liver function, particularly via the 13C-Methacetin Breath Test (MBT). It is not an approved therapeutic drug but is used in liver diagnostics to evaluate hepatic microsomal function and metabolic capacity.
Pharmacokinetic parameters from healthy adult volunteers (mean age ~30-35 years) following intravenous administration reported in diagnostic liver function testing studies.