.Pharmacolibrary.Drugs.ATC.V.V04CG30 .Pharmacolibrary.Drugs.ATC.V.V04CG30| name: | CaffeineAndSodiumBenzoate | |
| ATC code: | V04CG30 | route: | intravenous |
| compartments: | 1 | |
| dosage: | 250 | mg |
| volume of distribution: | 35 | L |
| clearance: | 3.5 | L/h |
| other parameters in model implementation | ||
Caffeine and sodium benzoate is a combination drug that was historically used as a central nervous system stimulant and respiratory stimulant, particularly in cases of drug-induced depression or respiratory depression. This combination is no longer widely used and has largely been replaced by safer alternatives. Caffeine is a methylxanthine that acts as a stimulant, while sodium benzoate serves as a preservative and increases the solubility of caffeine for injection.
Estimated pharmacokinetic parameters for the IV administration of caffeine and sodium benzoate in healthy adults, based on known pharmacokinetic data for intravenous caffeine.