.Pharmacolibrary.Drugs.ATC.V.V04CH30 .Pharmacolibrary.Drugs.ATC.V.V04CH30| name: | AminohippuricAcid |
| ATC code: | V04CH30 | route: | intravenous |
| n-compartments | 1 |
Aminohippuric acid (also known as para-aminohippuric acid, PAH) is an organic acid historically used as a diagnostic agent to measure renal plasma flow and renal function. It is not approved or used today as a therapeutic drug.
Adults, healthy volunteers. Classic renal clearance and renal plasma flow tests, intravenous bolus administration.
Dhondt, L, et al., & Devreese, M (2020). Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model. Frontiers in pharmacology 11 607101–None. DOI:10.3389/fphar.2020.607101 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33574754
Dubinsky, S, et al., & Edginton, A (2022). Determining the Effects of Chronic Kidney Disease on Organic Anion Transporter1/3 Activity Through Physiologically Based Pharmacokinetic Modeling. Clinical pharmacokinetics 61(7) 997–1012. DOI:10.1007/s40262-022-01121-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35508593
Dhondt, L, et al., & Devreese, M (2021). The Development of a Juvenile Porcine Augmented Renal Clearance Model Through Continuous Infusion of Lipopolysaccharides: An Exploratory Study. Frontiers in veterinary science 8 639771–None. DOI:10.3389/fvets.2021.639771 PUBMED:https://pubmed.ncbi.nlm.nih.gov/33996970