.Pharmacolibrary.Drugs.ATC.V.V08DA04 .Pharmacolibrary.Drugs.ATC.V.V08DA04| name: | PerflutrenPhospholipidMicrospheres | |
| ATC code: | V08DA04 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 10 | mg |
| volume of distribution: | 0.16 | L |
| clearance: | 0.13 | L/kg/min |
| other parameters in model implementation | ||
Perflutren, phospholipid microspheres (commercially known as DEFINITY) are injectable ultrasound contrast agents used to enhance echocardiographic imaging by improving delineation of cardiac chambers and endocardial borders. The agent consists of microspheres filled with perflutren gas encapsulated by a phospholipid shell. It is approved for clinical use in many countries for diagnostic imaging.
Pharmacokinetic parameters reported in healthy adult volunteers after intravenous bolus and infusion dosing.