name: | Fluoroestradiol18f | |
ATC code: | V09IX11 | route: | intravenous |
compartments: | 2 | |
dosage: | 222 | mg |
volume of distribution: | 1.8 | L |
clearance: | 0.22 | L/min |
other parameters in model implementation |
Fluoroestradiol (18F), also known as 18F-FES, is a radioactive diagnostic agent used in positron emission tomography (PET) imaging to assess estrogen receptor-positive (ER+) breast cancer lesions. It is not a therapeutic agent, but rather an imaging tracer. Approved by the FDA in 2020 for imaging ER+ lesions in patients with recurrent or metastatic breast cancer.
Typical adult female oncology patients (breast cancer, both metastatic and recurrent), healthy volunteers; data obtained using non-compartmental analysis and two-compartmental models.