name: | TositumomabIodine131iTositumomab |
ATC code: | V10XA53 | route: | intravenous |
n-compartments | 2 |
Tositumomab/iodine (131I) tositumomab is a radiolabeled monoclonal antibody formerly used for the treatment of rituximab-refractory, CD20-positive, follicular non-Hodgkin's lymphoma. It combines the murine anti-CD20 IgG2a monoclonal antibody (tositumomab) with radioactive iodine-131 to target malignant B lymphocytes. The drug has been withdrawn from the market and is no longer approved for use.
Pharmacokinetic parameters in adult patients with relapsed or refractory non-Hodgkin's lymphoma; typical values in adults from various clinical reports.