name: | Miconazole |
ATC code: | A01AB09 | route: | oral |
n-compartments | 1 |
Miconazole is an imidazole antifungal agent used to treat fungal infections, particularly those caused by Candida and dermatophytes. It is commonly employed for oral, oropharyngeal, and topical fungal infections. Miconazole is approved and prescribed for oropharyngeal candidiasis (oral thrush) as well as skin mycoses, and is widely available in topical and oral gel formulations.
Pharmacokinetic parameters for adult healthy volunteers after repeated oral administration of miconazole oral gel.
Simmons, KB, et al., & Merkatz, R (2018). Effects of concurrent vaginal miconazole treatment on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol delivered from a contraceptive vaginal ring: a randomized, crossover drug-drug interaction study. Contraception 97(3) 270–276. DOI:10.1016/j.contraception.2017.10.010 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29097225
Lalla, RV, & Bensadoun, RJ (2011). Miconazole mucoadhesive tablet for oropharyngeal candidiasis. Expert review of anti-infective therapy 9(1) 13–17. DOI:10.1586/eri.10.152 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21171872
Hayashi, Y, et al., & Yamada, Y (1995). [Study of serial bronchoalveolar lavage in patients with aspergilloma: cell reaction at the affected sites and penetration of miconazole and flucytosine into the lesion]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 69(5) 517–523. DOI:10.11150/kansenshogakuzasshi1970.69.517 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7602184