.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A01A_StomatologicalPreparations.A01AB13_Tetracycline.Tetracycline

Information

name:Tetracycline
ATC code:A01AB13
route:oral
n-compartments1

Tetracycline is a broad-spectrum antibiotic used to treat a wide array of bacterial infections, including respiratory tract infections, urinary tract infections, and certain sexually transmitted diseases. It works by inhibiting protein synthesis in bacteria. Though widely used in the past, tetracycline use has declined due to bacterial resistance and newer antibiotics. It is still sometimes prescribed today, but more modern tetracyclines are generally preferred.

Pharmacokinetics

Reported population pharmacokinetic parameters in healthy adult volunteers, generally after oral administration.

References

  1. Tao, RE, et al., & Feldman, SR (2023). Oral Tetracycline-Class Drugs in Dermatology: Impact of Food Intake on Absorption and Efficacy. Antibiotics (Basel, Switzerland) 12(7) –. DOI:10.3390/antibiotics12071152 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37508248

  2. Thompson, EJ, et al., & Hornik, CP (2019). Population Pharmacokinetics of Doxycycline in Children. Antimicrobial agents and chemotherapy 63(12) –. DOI:10.1128/AAC.01508-19 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31548185

  3. Rodvold, KA, et al., & Pai, MP (2020). Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics. Clinical pharmacokinetics 59(4) 409–425. DOI:10.1007/s40262-019-00843-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31773505

Revisions


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