name: | CimetidineAndAntacidsCombinations |
ATC code: | A02AA10 | route: | oral |
n-compartments | 1 |
This combination combines cimetidine, a histamine H2-receptor antagonist that inhibits gastric acid secretion, with antacids that neutralize existing stomach acidity. It was used for short-term treatment of duodenal ulcers and relief of heartburn due to acid indigestion. This particular combination is largely discontinued and is not widely approved or marketed today.
Pharmacokinetic estimates reported for a typical healthy adult population. No specific study found for the exact combination formulation; the PK values provided are based on cimetidine monotherapy, as antacids generally do not modify cimetidine kinetics substantially.