.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A02B_DrugsForPepticUlcerAndGastroOesophagealRefluxDis.A02BD04_PantoprazoleAmoxicillinA.PantoprazoleAmoxicillinA .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A02B_DrugsForPepticUlcerAndGastroOesophagealRefluxDis.A02BD04_PantoprazoleAmoxicillinA.PantoprazoleAmoxicillinA| name: | PantoprazoleAmoxicillinAndClarithromycin | |
| ATC code: | A02BD04 | route: | oral |
| compartments: | 1 | |
| dosage: | 1540 | mg |
| volume of distribution: | 25 | L |
| clearance: | 15 | L/h |
| other parameters in model implementation | ||
A fixed-dose combination used for eradication of Helicobacter pylori infection and treatment of peptic ulcer disease, comprising a proton pump inhibitor (pantoprazole) and two antibiotics (amoxicillin and clarithromycin). This combination is approved and widely used as standard triple therapy.
Estimated population pharmacokinetic parameters for the oral co-administration of pantoprazole 40 mg, amoxicillin 1000 mg, and clarithromycin 500 mg, twice daily in healthy adults, based on available literature of individual components.