name: | PantoprazoleAmoxicillinAndClarithromycin |
ATC code: | A02BD04 | route: | oral |
n-compartments | 1 |
A fixed-dose combination used for eradication of Helicobacter pylori infection and treatment of peptic ulcer disease, comprising a proton pump inhibitor (pantoprazole) and two antibiotics (amoxicillin and clarithromycin). This combination is approved and widely used as standard triple therapy.
Estimated population pharmacokinetic parameters for the oral co-administration of pantoprazole 40 mg, amoxicillin 1000 mg, and clarithromycin 500 mg, twice daily in healthy adults, based on available literature of individual components.