.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A02B_DrugsForPepticUlcerAndGastroOesophagealRefluxDis.A02BX02_Sucralfate.Sucralfate

Information

name:Sucralfate
ATC code:A02BX02
route:oral
n-compartments1

Sucralfate is a cytoprotective agent used primarily to treat and prevent ulcers in the gastrointestinal tract, especially duodenal ulcers. It acts locally by forming a protective barrier at ulcer sites and does not have significant systemic absorption. Sucralfate is currently approved and widely used for gastroduodenal ulcer management.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adults administered standard oral doses, based on available pharmacological knowledge and product labels indicating minimal systemic absorption.

References

  1. Brouwers, JR, & de Smet, PA (1994). Pharmacokinetic-pharmacodynamic drug interactions with nonsteroidal anti-inflammatory drugs. Clinical pharmacokinetics 27(6) 462–485. DOI:10.2165/00003088-199427060-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7882636

Revisions


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