.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A03C_AntispasmodicsInCombinationWithPsycholeptics.A03CB04_HomatropineMethylbromide.HomatropineMethylbromide .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A03C_AntispasmodicsInCombinationWithPsycholeptics.A03CB04_HomatropineMethylbromide.HomatropineMethylbromide| name: | HomatropineMethylbromideAndPsycholeptics | |
| ATC code: | A03CB04 | route: | oral |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 120 | mL/min |
| other parameters in model implementation | ||
Combination drug containing homatropine methylbromide, a muscarinic antagonist used for gastrointestinal disorders, and various psycholeptics such as barbiturates. Historically used to treat peptic ulcers and GI spasms with additional sedative/anti-anxiety effects. Not widely used or approved in most modern formularies today.
No published human pharmacokinetic studies available for the combination of homatropine methylbromide and psycholeptics. Monographs for oral homatropine methylbromide were used for estimation in healthy adults.