.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AC06_Methylcellulose.Methylcellulose .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AC06_Methylcellulose.Methylcellulose| name: | Methylcellulose |
| ATC code: | A06AC06 | route: | oral |
| n-compartments | 1 |
Methylcellulose is a semi-synthetic, inert, hydrophilic compound derived from cellulose. It is used primarily as a bulk-forming laxative to treat constipation and to promote regular bowel movements. Methylcellulose is currently approved and in widespread clinical use as an over-the-counter oral laxative. It is also used as a food additive and in pharmaceutical formulations as a thickener or emulsifier.
No relevant pharmacokinetic (PK) studies in humans reporting systemic absorption or standard PK parameters (such as volume of distribution, clearance, or bioavailability), since methylcellulose is recognized as not systemically absorbed in the gastrointestinal (GI) tract when administered orally as a laxative. All parameters estimated based on its clinical pharmacology and non-absorption.
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