.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AC07_TriticumWheatFibre.TriticumWheatFibre .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AC07_TriticumWheatFibre.TriticumWheatFibre| name: | TriticumWheatFibre |
| ATC code: | A06AC07 | route: | oral |
| n-compartments | 1 |
Triticum (wheat fibre) is a dietary fibre derived from wheat, classified as a bulk-forming laxative. It is used to treat constipation and to promote bowel regularity by increasing stool bulk. It is available as an over-the-counter supplement and is considered safe for general use, though not indicated for acute or severe constipation or in patients with intestinal obstruction. It is approved for use as a dietary supplement rather than as a prescription medication.
No published pharmacokinetic studies reporting absorption, distribution, metabolism, or excretion of wheat fibre as an active pharmacologically absorbed substance in humans. Dietary fibre is generally considered non-absorbable; pharmacokinetic parameters such as volume of distribution, clearance, and bioavailability are not typically defined for this agent.
Marklund, M, et al., & Kamal-Eldin, A (2013). Chain length of dietary alkylresorcinols affects their in vivo elimination kinetics in rats. The Journal of nutrition 143(10) 1573–1578. DOI:10.3945/jn.113.178392 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23946349