.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AX08_Tenapanor.Tenapanor .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A06A_DrugsForConstipation.A06AX08_Tenapanor.Tenapanor| name: | Tenapanor | |
| ATC code: | A06AX08 | route: | oral |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | L/h |
| other parameters in model implementation | ||
Tenapanor is an inhibitor of the sodium/hydrogen exchanger 3 (NHE3) located in the intestines, approved for the treatment of adults with irritable bowel syndrome with constipation (IBS-C) and, in some regions, for hyperphosphatemia in chronic kidney disease patients on dialysis.
Healthy adults, both sexes, evaluated after oral administration; tenapanor has minimal systemic absorption, thus systemic exposure is negligible.