.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07A_IntestinalAntiinfectives.A07AA02_Nystatin.Nystatin

Information

name:Nystatin
ATC code:A07AA02
route:oral
compartments:1
dosage:500000mg
volume of distribution:1L
clearance:0L/h
other parameters in model implementation

Nystatin is a polyene antifungal antibiotic used primarily for the treatment of Candida infections of the skin, oral cavity, and gastrointestinal tract. It is not systemically absorbed and is commonly administered as oral suspension, tablets, or topical preparations. Nystatin remains an approved medication for local treatment of Candida infections.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adult subjects after oral administration, based on published reviews and product information; systemic absorption is negligible.

References

  1. Bender, JF, et al., & Wiernik, PH (1979). Role of vancomycin as a component of oral nonabsorbable antibiotics for microbial suppression in leukemic patients. Antimicrobial agents and chemotherapy 15(3) 455–460. DOI:10.1128/AAC.15.3.455 PUBMED:https://pubmed.ncbi.nlm.nih.gov/464573

Revisions


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