.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07A_IntestinalAntiinfectives.A07AA09_Vancomycin.Vancomycin .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07A_IntestinalAntiinfectives.A07AA09_Vancomycin.Vancomycin| name: | Vancomycin |
| ATC code: | A07AA09 | route: | intravenous |
| n-compartments | 2 |
Vancomycin is a glycopeptide antibiotic that is used for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant Staphylococcus aureus (MRSA) and other Gram-positive bacteria. It is especially used when other antibiotics are ineffective or contraindicated. Vancomycin is approved by major regulatory agencies and is widely used in clinical practice today.
Typical pharmacokinetic parameters for adult patients with normal renal function receiving intravenous vancomycin therapy.
Goyal, RK, et al., & Al Mohajer, M (2022). Population Pharmacokinetics of Vancomycin in Pregnant Women. Frontiers in pharmacology 13 873439–None. DOI:10.3389/fphar.2022.873439 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35734401
Chen, Z, et al., & Liebchen, U (2023). Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial agents and chemotherapy 67(6) e0024123–None. DOI:10.1128/aac.00241-23 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37162349
Yu, Z, et al., & Zhao, Y (2023). Population pharmacokinetics and individualized dosing of vancomycin for critically ill patients receiving continuous renal replacement therapy: the role of residual diuresis. Frontiers in pharmacology 14 1298397–None. DOI:10.3389/fphar.2023.1298397 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38223197