.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07A_IntestinalAntiinfectives.A07AA13_Rifamycin.Rifamycin

Information

Rifamycin is a broad-spectrum antibiotic belonging to the rifamycin group, primarily used for the treatment of gastrointestinal infections such as travelers’ diarrhea caused by noninvasive strains of Escherichia coli. Unlike rifampin, rifamycin (A07AA13) is administered orally as a non-absorbed antimicrobial agent and is approved for use in several countries for this indication.

Pharmacokinetics

Adult healthy volunteers, both sexes; single oral dose of rifamycin SV tablets

References

1. Hoy, SM (2019). Rifamycin SV MMX. Clinical drug investigation 39(7) 691–697. DOI:10.1007/s40261-019-00808-2 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31172447

2. Scarpignato, C, & Pelosini, I (2005). Rifaximin, a poorly absorbed antibiotic: pharmacology and clinical potential. Chemotherapy 51 Suppl 1 36–66. DOI:10.1159/000081990 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15855748

3. Zheng, C, et al., & Gao, F (2017). Clinical and pharmacological hallmarks of rifapentine's use in diabetes patients with active and latent tuberculosis: do we know enough?. Drug design, development and therapy 11 2957–2968. DOI:10.2147/DDDT.S146506 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29066867

Revisions

• 06/2025 initial generated model