.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07B_IntestinalAdsorbents.A07BC01_Pectin.Pectin

Information

name:Pectin
ATC code:A07BC01
route:oral
n-compartments1

Pectin is a complex polysaccharide derived from plant cell walls, primarily citrus fruits and apples. It is used as a dietary fiber and functional food ingredient, and has been employed pharmaceutically as an antidiarrheal agent (often in combination with kaolin) to treat mild diarrhea. It is not commonly used as a prescription medication for this purpose today, as more effective agents are available.

Pharmacokinetics

No known published studies provide quantitative pharmacokinetic (PK) parameters for pectin in humans, as it is a non-absorbable polymer acting locally in the gastrointestinal tract. Thus, pharmacokinetic parameters are not applicable to typical systemic PK models.

References

  1. Pereyra, RB, & Gonzalez Vidal, NL (2024). Amiodarone chewable gels as a potential appproach for paediatric congenital cardiopathies treatment: Comparison between animal and vegetal gelling agents. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 201 114370–None. DOI:10.1016/j.ejpb.2024.114370 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38880402

  2. Musa, N, & Wong, TW (2020). Design of polysaccharidic nano-in-micro soft agglomerates as primary oral drug delivery vehicle for colon-specific targeting. Carbohydrate polymers 247 116673–None. DOI:10.1016/j.carbpol.2020.116673 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32829801

Revisions


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