name: | Prednisolone | |
ATC code: | A07EA01 | route: | oral |
compartments: | 2 | |
dosage: | 20 | mg |
volume of distribution: | 0.58 | L |
clearance: | 0.23 | L/h/kg |
other parameters in model implementation |
Prednisolone is a synthetic glucocorticoid used as an anti-inflammatory and immunosuppressive agent in the treatment of various conditions, including allergic disorders, autoimmune diseases, and inflammatory conditions. It is approved for clinical use and remains a widely prescribed corticosteroid.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral administration.
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Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270
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