.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07E_IntestinalAntiinflammatoryAgents.A07EC04_Balsalazide.Balsalazide .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A07E_IntestinalAntiinflammatoryAgents.A07EC04_Balsalazide.Balsalazide| name: | Balsalazide | |
| ATC code: | A07EC04 | route: | oral |
| compartments: | 1 | |
| dosage: | 2250 | mg |
| volume of distribution: | 15 | L |
| clearance: | 12 | L/hr |
| other parameters in model implementation | ||
Balsalazide is an anti-inflammatory drug belonging to the class of aminosalicylates, used primarily in the treatment of mild-to-moderate ulcerative colitis. It is a prodrug that releases mesalazine (5-aminosalicylic acid, 5-ASA) in the colon. Balsalazide is approved for use in the United States and certain other regions.
Pharmacokinetic parameters estimated for healthy adult volunteers after oral administration.
Tursi, A (2009). Balsalazide in treating colonic diseases. Expert opinion on drug metabolism & toxicology 5(12) 1555–1563. DOI:10.1517/17425250903228842 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19708827