name: | EphedrineCombinations | |
ATC code: | A08AA56 | route: | oral |
compartments: | 1 | |
dosage: | 50 | mg |
volume of distribution: | 1.8 | L |
clearance: | 105 | mL/min |
other parameters in model implementation |
Ephedrine is a sympathomimetic amine used primarily as a decongestant, bronchodilator, and for the treatment of hypotension, especially during anesthesia. It is no longer commonly used as a primary therapeutic agent in many countries due to the availability of safer alternatives, but it is still found in some over-the-counter products in combination with other agents for weight loss and nasal decongestion.
Pharmacokinetic parameters estimated for a standard adult population (both sexes, aged 18-65, without hepatic or renal impairment) assuming oral administration, as no specific published PK study is available for ephedrine in combination (A08AA56) products.