name: | InsulinHuman | |
ATC code: | A10AF01 | route: | subcutaneous |
compartments: | 2 | |
dosage: | 0.1 | mg |
volume of distribution: | 0.06 | L |
clearance: | 1.2 | mL/min/kg |
other parameters in model implementation |
Insulin (human) is a peptide hormone used for the treatment of diabetes mellitus, both type 1 and type 2. It lowers blood glucose by facilitating cellular glucose uptake and is an essential hormone therapy in insulin-dependent diabetes. Approved and widely used in clinical practice today.
Pharmacokinetic parameters for subcutaneous administration in healthy adult volunteers. Values represent averages from published literature.
Setji, TL, et al., & Feinglos, MN (2016). Technosphere insulin: inhaled prandial insulin. Expert opinion on biological therapy 16(1) 111–117. DOI:10.1517/14712598.2016.1121230 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26567896