.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BA02_Metformin.Metformin_1

Information

name:Metformin_1
ATC code:A10BA02_1
route:oral
n-compartments2

Metformin is an oral antihyperglycemic of the biguanide class, used in the treatment of type 2 diabetes mellitus; it is still widely used and approved as first-line therapy.

Pharmacokinetics

Pharmacokinetic parameters in patients with renal impairment compared to healthy subjects.

References

  1. Graham, GG, et al., & Williams, KM (2011). Clinical pharmacokinetics of metformin. Clinical pharmacokinetics 50(2) 81–98. DOI:10.2165/11534750-000000000-00000 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21241070

  2. Scheen, AJ (1996). Clinical pharmacokinetics of metformin. Clinical pharmacokinetics 30(5) 359–371. DOI:10.2165/00003088-199630050-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8743335

  3. Dhillon, S (2019). Dapagliflozin: A Review in Type 2 Diabetes. Drugs 79(10) 1135–1146. DOI:10.1007/s40265-019-01148-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31236801

Revisions


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