.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BB05_Tolazamide.Tolazamide .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BB05_Tolazamide.Tolazamide| name: | Tolazamide | |
| ATC code: | A10BB05 | route: | oral |
| compartments: | 1 | |
| dosage: | 250 | mg |
| volume of distribution: | 9 | L |
| clearance: | 1.1 | L/h |
| other parameters in model implementation | ||
Tolazamide is a first-generation sulfonylurea oral hypoglycemic agent used for the management of type 2 diabetes mellitus. It stimulates pancreatic beta cells to release insulin. Tolazamide was widely used in the past but has largely been replaced by newer agents; however, it is still approved for clinical use in some regions.
Pharmacokinetic parameters are estimated for healthy adult subjects after single oral dosing, based on available secondary literature summaries and standard references.