.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BB06_Carbutamide.Carbutamide .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BB06_Carbutamide.Carbutamide| name: | Carbutamide | |
| ATC code: | A10BB06 | route: | oral |
| compartments: | 1 | |
| dosage: | 500 | mg |
| volume of distribution: | 16 | L |
| clearance: | 1.5 | L/h |
| other parameters in model implementation | ||
Carbutamide is a first-generation sulfonylurea oral hypoglycemic drug historically used to treat type 2 diabetes mellitus. It acts by stimulating insulin secretion from pancreatic beta-cells. Carbutamide is largely obsolete and is not commonly used in clinical practice today due to safer alternatives with better efficacy and lower risk of adverse effects.
Pharmacokinetic parameters estimated for a typical adult (based on pharmacological class analogs and limited historical data). No recent or direct human PK studies with full parameterization are available for carbutamide.