.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BB07_Glipizide.Glipizide_1

Information

name:Glipizide_1
ATC code:A10BB07_1
route:oral
n-compartments2

Glipizide is an oral sulfonylurea antidiabetic drug used in the management of type 2 diabetes mellitus. It stimulates insulin secretion by the pancreas and is approved for use worldwide.

Pharmacokinetics

Population pharmacokinetic study in adult patients with type 2 diabetes, reported as a two-compartment model.

References

  1. Khan, H, et al., & Rasool, MF (2025). Clinical pharmacokinetics of glipizide: a systematic review. Expert opinion on drug metabolism & toxicology 21(1) 69–79. DOI:10.1080/17425255.2024.2402478 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39267225

  2. Kim, NT, et al., & Lee, SY (2022). Effects of CYP2C9*3 and *13 alleles on the pharmacokinetics and pharmacodynamics of glipizide in healthy Korean subjects. Archives of pharmacal research 45(2) 114–121. DOI:10.1007/s12272-021-01366-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/34952963

  3. Kirchheiner, J, et al., & Brockmöller, J (2005). Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. Clinical pharmacokinetics 44(12) 1209–1225. DOI:10.2165/00003088-200544120-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16372821

Revisions


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