.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BD03_MetforminAndRosiglitazon.MetforminAndRosiglitazon .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BD03_MetforminAndRosiglitazon.MetforminAndRosiglitazon| name: | MetforminAndRosiglitazone |
| ATC code: | A10BD03 | route: | oral |
| n-compartments | 1 |
Metformin and rosiglitazone is a fixed-dose combination oral medication used for the management of type 2 diabetes mellitus. Metformin is a biguanide that decreases hepatic glucose production and improves insulin sensitivity, while rosiglitazone is a thiazolidinedione that enhances insulin sensitivity in peripheral tissues. The combination is approved for use in several countries to improve glycemic control in adults with type 2 diabetes.
Population pharmacokinetics in healthy adults and patients with type 2 diabetes. Parameters are reported from studies involving oral administration of the fixed-dose combination tablet (metformin 500 mg/rosiglitazone 2 mg) in adults.