.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BF01_Acarbose.Acarbose

Information

name:Acarbose
ATC code:A10BF01
route:oral
n-compartments1

Acarbose is an oral alpha-glucosidase inhibitor used to treat type 2 diabetes mellitus. It works by delaying the digestion and absorption of carbohydrates in the small intestine, thereby reducing postprandial blood glucose levels. It is approved and widely used for glycemic control in patients with diabetes.

Pharmacokinetics

Pharmacokinetic parameters from healthy adult volunteers, after oral administration.

References

  1. Scheen, AJ, & Lefèbvre, PJ (1995). Antihyperglycaemic agents. Drug interactions of clinical importance. Drug safety 12(1) 32–45. DOI:10.2165/00002018-199512010-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7741982

  2. Balaich, J, et al., & Donia, MS (2021). The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature 600(7887) 110–115. DOI:10.1038/s41586-021-04091-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34819672

  3. Jennings, PE (1997). Oral antihyperglycaemics. Considerations in older patients with non-insulin-dependent diabetes mellitus. Drugs & aging 10(5) 323–331. DOI:10.2165/00002512-199710050-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9143853

Revisions


Generated at 2025-07-21T18:21:10Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos