.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BF02_Miglitol.Miglitol .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A10B_BloodGlucoseLoweringDrugsExclInsulins.A10BF02_Miglitol.Miglitol| name: | Miglitol | |
| ATC code: | A10BF02 | route: | oral |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.18 | L |
| clearance: | 150 | mL/min |
| other parameters in model implementation | ||
Miglitol is an oral antidiabetic drug, classified as an alpha-glucosidase inhibitor. It delays the absorption of carbohydrates from the intestines, thus reducing postprandial blood glucose levels. Miglitol is approved and used today mainly as adjunct therapy in type 2 diabetes mellitus management.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral dose administration.
Kadokura, T, et al., & Smulders, R (2014). Clinical pharmacokinetics and pharmacodynamics of the novel SGLT2 inhibitor ipragliflozin. Clinical pharmacokinetics 53(11) 975–988. DOI:10.1007/s40262-014-0180-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/25316572