name: | Calcitriol_1 |
ATC code: | A11CC04_1 | route: | oral |
n-compartments | 2 |
Calcitriol is the hormonally active form of vitamin D3 (1,25-dihydroxycholecalciferol), used in the management of hypocalcemia and bone disorders associated with chronic renal failure, hypoparathyroidism, and some other conditions. It is approved and commonly used clinically.
Pharmacokinetics of calcitriol in healthy adult volunteers after single oral administration.
Linglart, A, et al., & Carpenter, TO (2022). Sustained Efficacy and Safety of Burosumab, a Monoclonal Antibody to FGF23, in Children With X-Linked Hypophosphatemia. The Journal of clinical endocrinology and metabolism 107(3) 813–824. DOI:10.1210/clinem/dgab729 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34636899
Moe, SM, et al., & Peacock, M (1998). Safety and efficacy of pulse and daily calcitriol in patients on CAPD: a randomized trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 13(5) 1234–1241. DOI:10.1093/ndt/13.5.1234 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9623560
Best, CM, et al., & O'Brien, KO (2022). Vitamin D kinetics in nonpregnant and pregnant women after a single oral dose of trideuterated vitamin D. The Journal of steroid biochemistry and molecular biology 216 106034–None. DOI:10.1016/j.jsbmb.2021.106034 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34843870