.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A11C_VitaminAAndDInclCombinationsOfTheTwo.A11CC20_CalciumAndVitaminDCombin.CalciumAndVitaminDCombin .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A11C_VitaminAAndDInclCombinationsOfTheTwo.A11CC20_CalciumAndVitaminDCombin.CalciumAndVitaminDCombin| name: | CalciumAndVitaminDCombinations |
| ATC code: | A11CC20 | route: | oral |
| n-compartments | 1 |
This combination comprises calcium salts (commonly calcium carbonate or calcium citrate) with vitamin D (mostly cholecalciferol or ergocalciferol). It is used for the prevention and treatment of calcium and vitamin D deficiency states, osteoporosis, and as a supplement in elderly populations. The combination is approved and widely used today.
Pharmacokinetics in healthy adult volunteers for a typical tablet containing 500 mg calcium (as carbonate) and 400 IU (10 micrograms) cholecalciferol, oral administration.
Jones, KS, et al., & Schoenmakers, I (2014). 25(OH)D2 half-life is shorter than 25(OH)D3 half-life and is influenced by DBP concentration and genotype. The Journal of clinical endocrinology and metabolism 99(9) 3373–3381. DOI:10.1210/jc.2014-1714 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24885631