name: | ColecalciferolCombinations |
ATC code: | A11CC55 | route: | oral |
n-compartments | 1 |
Colecalciferol (vitamin D3), often used in combination with other vitamins and minerals, is a fat-soluble vitamin primarily used for the prevention and treatment of vitamin D deficiency, rickets, and certain bone disorders. Combinations may be indicated in cases where multiple nutrient deficiencies are addressed. It is an approved and commonly used medication and supplement globally.
Pharmacokinetic parameters estimated for a typical healthy adult population, as no direct clinical PK publications for colecalciferol combinations could be identified.
Jones, KS, et al., & Schoenmakers, I (2014). 25(OH)D2 half-life is shorter than 25(OH)D3 half-life and is influenced by DBP concentration and genotype. The Journal of clinical endocrinology and metabolism 99(9) 3373–3381. DOI:10.1210/jc.2014-1714 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24885631