.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A12C_OtherMineralSupplements.A12CC10_MagnesiumOxide.MagnesiumOxide

Information

name:MagnesiumOxide
ATC code:A12CC10
route:oral
n-compartments1

Magnesium oxide is an inorganic compound commonly used as a mineral supplement to prevent or treat low levels of magnesium in the body. It can also be used as an antacid to relieve heartburn, sour stomach, or acid indigestion, and as a laxative for short-term, rapid emptying of the bowel. It is an approved medication, available over-the-counter in many countries.

Pharmacokinetics

Estimated pharmacokinetic parameters for adult healthy individuals after typical oral administration, as there are no published detailed compartmental PK models for magnesium oxide using this ATC code. Values are based on published general information on magnesium absorption kinetics.

References

  1. Kashihara, Y, et al., & Ieiri, I (2019). Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation. European journal of clinical pharmacology 75(3) 351–361. DOI:10.1007/s00228-018-2568-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30382297

  2. Hoy, SM, et al., & Wagstaff, AJ (2009). Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser. Drugs 69(1) 123–136. DOI:10.2165/00003495-200969010-00009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19192941

  3. Schuette, SA, et al., & Janghorbani, M (1994). Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection. JPEN. Journal of parenteral and enteral nutrition 18(5) 430–435. DOI:10.1177/0148607194018005430 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7815675

Revisions


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