.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AA01_Levocarnitine.Levocarnitine .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AA01_Levocarnitine.Levocarnitine| name: | Levocarnitine |
| ATC code: | A16AA01 | route: | intravenous |
| n-compartments | 2 |
Levocarnitine (L-carnitine) is a naturally occurring amino acid derivative that facilitates the transport of long-chain fatty acids into mitochondria for beta-oxidation. It is used in the treatment of primary and secondary carnitine deficiency in adults and children, and is approved for conditions such as end-stage renal disease on hemodialysis, inborn errors of metabolism, and other conditions where carnitine deficiency has been diagnosed.
Pharmacokinetic parameters in healthy adult volunteers after single intravenous dose.
Jennaro, TS, et al., & Stringer, KA (2023). Kidney function as a key driver of the pharmacokinetic response to high-dose L-carnitine in septic shock. Pharmacotherapy 43(12) 1240–1250. DOI:10.1002/phar.2882 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37775945