.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AA05_CarglumicAcid.CarglumicAcid .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AA05_CarglumicAcid.CarglumicAcid| name: | CarglumicAcid | |
| ATC code: | A16AA05 | route: | oral |
| compartments: | 1 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.4 | L |
| clearance: | 4.5 | mL/min/kg |
| other parameters in model implementation | ||
Carglumic acid is a structural analog of N-acetylglutamate used as an orphan drug for the treatment of hyperammonemia due to N-acetylglutamate synthase deficiency. It is approved for clinical use in multiple countries, including the US and EU.
Reported single-dose pharmacokinetics in healthy adult volunteers.