.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB12_ElosulfaseAlfa.ElosulfaseAlfa .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB12_ElosulfaseAlfa.ElosulfaseAlfa| name: | ElosulfaseAlfa |
| ATC code: | A16AB12 | route: | intravenous |
| n-compartments | 2 |
Elosulfase alfa is a recombinant form of human N-acetylgalactosamine 6-sulfatase (GALNS), indicated for the treatment of mucopolysaccharidosis IVA (MPS IVA, also known as Morquio A syndrome). It is an enzyme replacement therapy approved for use in patients with this rare, inherited, lysosomal storage disorder.
Pharmacokinetic parameters reported in pediatric and adult patients with MPS IVA following intravenous infusion of elosulfase alfa at 2 mg/kg once weekly over approximately 4 hours.