.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB25_OlipudaseAlfa.OlipudaseAlfa .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB25_OlipudaseAlfa.OlipudaseAlfa| name: | OlipudaseAlfa |
| ATC code: | A16AB25 | route: | intravenous |
| n-compartments | 2 |
Olipudase alfa is a recombinant human acid sphingomyelinase used as an enzyme replacement therapy for the treatment of non-central nervous system manifestations of acid sphingomyelinase deficiency (ASMD), also known as Niemann-Pick disease types A and B. It is approved for use in both pediatric and adult patients.
Pharmacokinetic parameters estimated for intravenous administration in adult and pediatric patients with ASMD. No comprehensive published PK models with full parameter reporting are available; estimates derived from available clinical and regulatory report information.