.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AX01_ThiocticAcid.ThiocticAcid .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AX01_ThiocticAcid.ThiocticAcid| name: | ThiocticAcid |
| ATC code: | A16AX01 | route: | oral |
| n-compartments | 1 |
Thioctic acid, also known as alpha-lipoic acid, is a naturally occurring compound with antioxidant properties. It is used mainly as a dietary supplement and has been investigated for use in diabetic neuropathy and as an adjunct in various metabolic or neurological disorders. It is not universally approved as a drug but is used as an over-the-counter supplement in many countries.
Pharmacokinetic parameters in healthy adults after oral administration of 600 mg thioctic acid.
Hermann, R, et al., & Gleiter, CH (1998). Gastric emptying in patients with insulin dependent diabetes mellitus and bioavailability of thioctic acid-enantiomers. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 6(1) 27–37. DOI:10.1016/s0928-0987(97)00065-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16256705
Peter, G, & Borbe, HO (1995). Absorption of [7,8-14C]rac-a-lipoic acid from in situ ligated segments of the gastrointestinal tract of the rat. Arzneimittel-Forschung 45(3) 293–299. PUBMED:https://pubmed.ncbi.nlm.nih.gov/7741788