name: | UridineTriacetate |
ATC code: | A16AX13 | route: | oral |
n-compartments | 1 |
Uridine triacetate is an orally administered prodrug of uridine used as an antidote for overdose or toxic reactions to fluorouracil or capecitabine chemotherapy. It is FDA-approved for emergency treatment within 96 hours of such overdoses or toxicity. Its pharmacological effect relies on increasing uridine levels to counteract toxicity.
Pharmacokinetic parameters estimated for healthy adults based on published summaries and secondary references. No detailed PK study found with population or compartmental parameters.