name: | Dicoumarol | |
ATC code: | B01AA01 | route: | oral |
compartments: | 1 | |
dosage: | 100 | mg |
volume of distribution: | 0.14 | L |
clearance: | 0.11 | L/kg/h |
other parameters in model implementation |
Dicoumarol is an oral anticoagulant of the coumarin type, historically used for the prevention and treatment of thromboembolic disorders. It acts as a vitamin K antagonist, inhibiting the synthesis of vitamin K-dependent clotting factors. Dicoumarol has largely been replaced by warfarin and is rarely used in modern medical practice.
Pharmacokinetic parameters reported in healthy adult volunteers following single oral dose administration.