.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AD11_Tenecteplase.Tenecteplase .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AD11_Tenecteplase.Tenecteplase| name: | Tenecteplase | |
| ATC code: | B01AD11 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 50 | mg |
| volume of distribution: | 6.2 | L |
| clearance: | 119 | mL/min |
| other parameters in model implementation | ||
Tenecteplase is a genetically engineered variant of tissue plasminogen activator (tPA) used as a thrombolytic agent. It is indicated primarily for the treatment of acute myocardial infarction (ST-segment elevation myocardial infarction, STEMI) to dissolve blood clots in coronary arteries. It is approved in many countries and used in hospital emergency settings.
Pharmacokinetic parameters reported in adult patients with acute myocardial infarction after a single intravenous bolus injection.