.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AX01_Defibrotide.Defibrotide .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AX01_Defibrotide.Defibrotide| name: | Defibrotide |
| ATC code: | B01AX01 | route: | intravenous |
| n-compartments | 2 |
Defibrotide is an oligonucleotide mixture derived from porcine intestinal mucosa, used primarily for the treatment of severe hepatic veno-occlusive disease (VOD) in patients undergoing hematopoietic stem cell transplantation. It is an approved medication in many countries for this indication and has antithrombotic, anti-ischemic, and anti-inflammatory properties.
Pharmacokinetic parameters are reported for adult patients with severe hepatic veno-occlusive disease after intravenous administration.