.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B02B_VitaminKAndOtherHemostatics.B02BD01_CoagulationFactorIxIiViiAndXInCo.CoagulationFactorIxIiViiAndXInCo .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B02B_VitaminKAndOtherHemostatics.B02BD01_CoagulationFactorIxIiViiAndXInCo.CoagulationFactorIxIiViiAndXInCo| name: | CoagulationFactorIxIiViiAndXInCombination |
| ATC code: | B02BD01 | route: | intravenous |
| n-compartments | 1 |
This combination is a prothrombin complex concentrate (PCC), comprised of human blood plasma-derived coagulation factors II, VII, IX, and X, typically used for the treatment and prevention of bleeding in patients with deficiency of multiple vitamin K-dependent clotting factors, such as in cases of warfarin reversal or hereditary deficiency. Prothrombin complex concentrates are still approved and in clinical use, such as in urgent reversal of anticoagulation.
Pharmacokinetic parameters are variably reported for individual factors, but specific PK for the 4-factor PCC combination limited. Data below are representative values estimated for adult populations from published summaries and product monographs.