.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B02B_VitaminKAndOtherHemostatics.B02BD10_VonWillebrandFactor.VonWillebrandFactor .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B02B_VitaminKAndOtherHemostatics.B02BD10_VonWillebrandFactor.VonWillebrandFactor| name: | VonWillebrandFactor |
| ATC code: | B02BD10 | route: | intravenous |
| n-compartments | 1 |
Von Willebrand factor (vWF) is a large multimeric glycoprotein important in hemostasis. It mediates platelet adhesion to sites of vascular injury and serves as a carrier protein for coagulation factor VIII. Plasma-derived and recombinant vWF products are used primarily in the treatment and prevention of bleeding episodes in patients with von Willebrand disease, a congenital or acquired bleeding disorder. vWF is an approved drug for clinical use today.
Pharmacokinetics in adults with severe von Willebrand disease following intravenous administration of plasma-derived von Willebrand factor concentrate (e.g., Wilate), using a one-compartment model.
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